Profile of the Running ES Score & Positions of GeneSet Members on the Rank Ordered List
| Dataset | Set_03_truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy.phenotype_truncNotch_versus_normalThy.cls #truncNotch_versus_normalThy_repos |
| Phenotype | phenotype_truncNotch_versus_normalThy.cls#truncNotch_versus_normalThy_repos |
| Upregulated in class | normalThy |
| GeneSet | BIOCARTA_MULTI-STEP REGULATION OF TRANSCRIPTION BY PITX2 |
| Enrichment Score (ES) | -0.78461754 |
| Normalized Enrichment Score (NES) | -1.4838858 |
| Nominal p-value | 0.02293578 |
| FDR q-value | 0.3913574 |
| FWER p-Value | 0.999 |
| PROBE | DESCRIPTION (from dataset) | GENE SYMBOL | GENE_TITLE | RANK IN GENE LIST | RANK METRIC SCORE | RUNNING ES | CORE ENRICHMENT | |
|---|---|---|---|---|---|---|---|---|
| 1 | NKD1 | 1340286 | 2986 | 0.167 | -0.1359 | No | ||
| 2 | PPP2R5D | 4010156 380408 5550112 5670162 | 3414 | 0.116 | -0.1418 | No | ||
| 3 | NKD2 | 1170731 | 4129 | 0.070 | -0.1698 | No | ||
| 4 | WIF1 | 7100184 | 4545 | 0.054 | -0.1842 | No | ||
| 5 | KREMEN2 | 110025 | 4970 | 0.042 | -0.2008 | No | ||
| 6 | FRAT1 | 780520 2120731 | 6113 | 0.022 | -0.2590 | No | ||
| 7 | PROC | 6520270 | 7230 | 0.013 | -0.3171 | No | ||
| 8 | DKK1 | 1940215 | 7528 | 0.011 | -0.3314 | No | ||
| 9 | DKK2 | 3610433 | 9536 | 0.004 | -0.4387 | No | ||
| 10 | FZD1 | 3140215 | 10613 | 0.001 | -0.4964 | No | ||
| 11 | PITX2 | 870537 2690139 | 10667 | 0.001 | -0.4992 | No | ||
| 12 | WNT1 | 4780148 | 12647 | -0.006 | -0.6047 | No | ||
| 13 | CSNK2A1 | 1580577 | 14708 | -0.041 | -0.7094 | No | ||
| 14 | LRP6 | 5130064 | 15253 | -0.075 | -0.7276 | No | ||
| 15 | DVL1 | 5900450 6510162 | 16314 | -0.219 | -0.7524 | Yes | ||
| 16 | LEF1 | 2470082 7100288 | 16790 | -0.347 | -0.7268 | Yes | ||
| 17 | CREBBP | 5690035 7040050 | 17020 | -0.421 | -0.6770 | Yes | ||
| 18 | HDAC1 | 2850670 | 17120 | -0.460 | -0.6146 | Yes | ||
| 19 | LDB1 | 5270601 | 17329 | -0.545 | -0.5455 | Yes | ||
| 20 | AXIN1 | 3360358 6940451 | 17501 | -0.629 | -0.4619 | Yes | ||
| 21 | GSK3B | 5360348 | 17827 | -0.830 | -0.3571 | Yes | ||
| 22 | CCND2 | 5340167 | 18568 | -2.711 | 0.0026 | Yes |
